Wolf's white should affect everyone 100% if what you are describing is correct. skill level higher than enemy level so it's 100% hit unless some hero has really high dodge (I have yet to see anyone to dodge wolf's white for my 2 years of playing DS except thief for obvious reasons).
I haven't fought vs lvl 150 yet so I'll sithere and listen if you don't mind.
If that would happen to me,I'd call that a bug, like Dragonslayers's flag not working against some certaing lines.
So, if something weird happens on GW, I change line immediately, never had weird s@#$ happend twice with different lines.